Modern labs must constantly adapt to cope with new analytical challenges and ever-increasing workloads, all while improving data confidence and reducing associated costs. This technical note highlights why time-of-flight mass spectrometry (TOF MS) is an ideal choice to address these challenges in both research and routine applications, by delivering fast, highly sensitive detection with full spectral information, for comprehensive sample characterisation in a single run.
TOF MS is one of the simplest and most powerful forms of mass spectrometry and uses the principle that when different ions are supplied with a given energy, the heavier ions will take longer to travel the fixed distance from the ion source to the detector. In contrast to conventional quadrupole mass spectrometers, which work by mass filtering, TOF instruments simultaneously analyse all ions. This makes them far less wasteful, and so inherently more sensitive.
In this technical note, we explore such advantages of TOF MS, specifically SepSolve’s BenchTOF2™ instruments, with examples for both research and routine applications.