Webinars

Non-target screening of complex samples is often hampered by challenges such as co-elutions and trace-level analytes, leading to low-confidence identifications or entirely missed compounds. Traditional one-dimensional GC–MS struggles to meet the demands of intricate petrochemical, food, and biological analyses, resulting in errors, inefficiencies, and lost insights. GCxGC–TOF MS overcomes these challenges with enhanced separation, reliable compound identification, and advanced data analysis tools.

This webinar demonstrates how GCxGC–TOF MS transforms non-target screening, with practical examples from sustainable fuel analysis, aroma profiling, and essential oil characterisation.

Volatile profiling of food and beverages is crucial for understanding and enhancing their quality, safety, and consumer appeal. Analysing these volatiles presents several challenges due to the diversity of chemical classes, their varying concentrations, and the complex matrices involved, which can be problematic for conventional gas chromatography–mass spectrometry (GC–MS) approaches.

Join Prof. Kieran Kilcawley, Principal Research Officer at Teagasc Food Research Centre and Adjunct Professor, University College Cork and Technological University Dublin, as he explores how innovative extraction and enrichment techniques, combined with state-of-the-art GC–MS analyses, can overcome these difficulties and deliver more detailed and accurate volatile profiles.

Discover how GCxGC-TOF MS is used, alongside advanced extraction techniques, to unravel the complexities of plant and food volatiles.

Speaker:

•  Luke Bell
  Lecturer in Temperate Horticulture, University of Reading, UK

This webinar shows how TD-GC×GC-TOF MS can provide detailed characterisation of complex odour and volatiles profiles from PCR resins, as well as confident taste and odour analysis of the packaged products.

Speakers:

• Shayne Green, Principal Research Scientist, Dow Inc.
• Peter Shimeall, Associate R&D Scientist, Dow Inc.

To coincide with the International Day of Women and Girls in Science 2024, SepSolve is hosting the 3rd annual e-seminar celebrating women in science. We will hear from leaders in their field about the use of GC across a host of application areas:

• Natasha D. Spadafora (University of Ferrara, Italy)
  A holistic approach to food quality assessment: The importance of combining comprehensive chemical and sensory analyses
• Twinkle Paryani (Abstrax Tech, USA)
  Identification of novel non-terpenoid compounds in cannabis using comprehensive GC×GC–FID/MS/SCD
• Helena Leask (SepSolve Analytical, UK)
  Exploring the flavour profiles of plant-based milk

The most essential part of a GC×GC system is the modulator, so it is important to choose the right device for the application.

Join this webinar to hear from Dr Laura McGregor, Product Marketing Manager at SepSolve Analytical, as she explores recent advances in GC×GC technology and how they are extending their capabilities from the niche to the mainstream.

Join us for this webinar, in conjunction with SelectScience, where we will describe how to overcome common challenges associated with sampling and analysing aroma volatiles using novel, automated extraction techniques combined with GC×GC–TOF MS and easy-to-use data analysis software. We’ll demonstrate this workflow for a range of food matrices, including protein powders, meat and dairy substitutes, and even plant-based ‘milk’ chocolate.

The global push towards a circular economy has resulted in an increase in the use of recycled materials to reduce waste, with manufacturers being urged to produce or use more post-consumer recycled (PCR) plastics, especially for food and beverage packaging.However, rigorous quality control (QC) is needed to ensure the recycled plastics do not produce volatile emissions that could be harmful or have a negative impact on the packaged product (e.g., malodours).

In this webinar, we demonstrate how to overcome low sensitivity, poor detection of compounds and slow processes when analysing recycled plastics for bad odours.

To coincide with the International Day of Women and Girls in Science 2023, SepSolve is hosting the 2nd annual e-seminar celebrating women in science. We will hear from leaders in their field about the use of GC across a host of application areas:

• Katelynn Perrault (Chaminade University, USA)
  Aromas of the ʻaina – GC×GC for Hawaiian natural products analysis
• Francesca De Falco (University of Plymouth, UK)
  Investigating the fate of microplastics in the environment by Py/TD-GCxGC-TOF MS: the case of biodegradable plastics
• Hilal Ezgi Toraman (Penn State University, USA)
  Comprehensive two-dimensional gas chromatography (GCxGC) method development for detailed characterization of pyrolysis oils

Learn how to overcome common problems associated with sampling volatiles from foods and beverages and how sensitivity can be improved using trap-enabled, extraction and enrichment methods like headspace, SPME, HiSorb high-capacity sorptive extraction and tube-based TD.

Explore how automated sample preparation combined with GC×GC–TOF MS can tackle complex samples that are out of reach for traditional GC–MS, and how data handling no longer needs to be the bottleneck of analytical workflows.

In this webinar, our guest speaker, Dr Nick Molden, (Emissions Analytics), demonstrates the use of thermal desorption (TD) for versatile sampling of emissions from exhausts, vehicle interiors and tyres.

When coupled with GCxGC–TOF MS this provides improved chemical fingerprinting of emissions to enhance our understanding of how vehicles may impact the environment and human health.

In this webinar, Dr Ken Scally (Suez), examines the challenges involved in Total Petroleum Hydrocarbon Criteria Working Group (TPH-CWG) analysis, and demonstrates the use of GCxGC–FID for thorough characterisation of both aliphatic and aromatic components in a single run, without the need for sample fractionation.

What the webinar covers:

• Hear about the challenges involved in TPH analysis for risk assessors
• Learn the basics of GC×GC and what it offers for analysis of TPH-CWG
• See how labour-intensive, offline sample fractionation can be eliminated, and GC–MS is no longer required for volatile petroleum hydrocarbon (VPH) methods.
• See how reduced sample preparation minimises the risk of error, while automated data-processing avoids operator subjectivity.

Join us for our series of short ‘bite-size’ webinars on “Latest innovations in mass spectrometry”.

In these three short 30-minute webinars, we explore the innovative technology behind the ground-breaking BenchTOF2 time-of-flight mass spectrometers and how their unparalleled performance in GC–MS can help your lab to discover more and deliver more.

Part 3: End-to-end workflows to solve problems in separation science

Do you struggle to get reliable answers from your MS data? Join us to learn how BenchTOF2 time-of-flight mass spectrometers can be integrated into discovery and routine workflows to fulfil your rapid return on investment goals.

Join us for our series of short ‘bite-size’ webinars on “Latest innovations in mass spectrometry”.

In these three short 30-minute webinars, we explore the innovative technology behind the ground-breaking BenchTOF2 time-of-flight mass spectrometers and how their unparalleled performance in GC–MS can help your lab to discover more and deliver more.

Part 2: How to benefit from soft ionisation without any compromise

Are you sure you always identify your compounds correctly? Join us to learn how BenchTOF2’s patented Tandem Ionisation provides an extra dimension of insight into sample composition, by providing both hard and soft ionisation simultaneously.

Join us for our series of short ‘bite-size’ webinars on “Latest innovations in mass spectrometry”.

In these three short 30-minute webinars, we explore the innovative technology behind the ground-breaking BenchTOF2 time-of-flight mass spectrometers and how their unparalleled performance in GC–MS can help your lab to discover more and deliver more.

Part 1: How to improve confidence in your GC–MS identifications

Have you ever wondered how you can get reference quality spectra from a time-of-flight MS? Join us to learn how BenchTOF instruments provide unparalleled spectral quality, improved mass accuracy and accurate isotope abundances – removing the guesswork and complexity commonly associated with analyte identification.

To coincide with the International Day of Women and Girls in Science (11 February 2022), SepSolve Analytical hosted a series of talks by female leaders in the field of gas chromatography. Each short talk focuses on a different application to demonstrate the range of uses for the technique.

• Rachael Szafnauer (Markes International, UK) – Flavour profiling of hard seltzers and identification of potential quality markers
• Giorgia Purcaro (University of Liège, Belgium) – Reverse fill/flush flow modulator in various GCxGC applications: a versatile tool to optimize your lab’s activities
• Melissa Dunkle (Dow Chemical, Netherlands) – Analysing pyrolysis oils using GCxGC
• Nadin Boegelsack (SepSolve Analytical, Canada) – Through the Fire and Flames - Addressing challenges in analyzing arson debris by implementing GCxGC–TOF MS
• Ilaria Belluomo (Imperial College London, UK) – Non-invasive detection of volatile biomarkers in neurological diseases

• Find out how thermal desorption (TD) provides sample security and integrity in breath biomarker workflows
• See how two-dimensional gas chromatography (GCxGC) allows you to discover more from breath samples
• Learn about the advantages of BenchTOF2 mass spectrometers for sensitive detection, confident identification and easy-to-use workflows
• See how smart software tools can automatically ‘spot the difference’ between breath profiles
• Hear about the real-world application of this technology for the detection of biomarkers associated with COVID-19.

• Discover how the value of GCxGC for fragrance profiling and how the addition of mass spectrometry provides deeper insights into sample composition, ensuring you do not miss any compound of relevance.
• Learn how Tandem Ionisation® can be used to improve confidence in isomer identification and enhance discovery-based workflows, and
• How smart software workflows can make use of all the raw data to automatically uncover the subtle differences between brand and imitation fragrances.

• Discover how BenchTOF2 removes the guesswork and complexity associated with compound identification, using an unbeatable combination of spectral fidelity, selectivity and smart software tools.
• Learn about the power of comprehensive analytical resolution – to gain deeper insights into sample composition and ensure you don’t miss any compound of relevance.
• See how intelligent, connected workflows allow BenchTOF2 to transition easily between discovery and routine applications within a unified user interface, saving time and improving productivity.

• Learn how to use chemometrics to spot the difference between complex samples, without having to be a statistics expert.
• Find out how alignment and raw data workflows leave no trace peaks overlooked.
• Hear how prediction models can be used to quickly and accurately classify future samples.

• See our simple workflows for GC and GCxGC processing on a range of file formats.
• Hear about streamlined instrument control and data processing.
• Find out how our network licensing can unify lab processing.

• Learn about the Centri platform for fully-automated, multi-mode sample preparation.
• Understand how trapping technology can extend system performance.
• See how GCxGC can reveal hidden information for complex samples.

• Learn the basics of GCxGC and what it offers for analysis of TPH-CWG.
• See how eliminating offline sample fractionation can reduce costs and analysis time.
• Hear about the productivity advantages of dual-channel GCxGC-FID.

• Learn the basics of GCxGC and what it offers over and above standard GC.
• Hear about how GCxGC-FID can provide robust and simple profiling of terpenes.
• See how mass spectrometry can help to differentiate cannabis strains.

• Find out how thermal desorption provides sample security and integrity in breath biomarker workflows.
• See how two-dimensional GC allows you to discover more from your samples.
• Learn about the advantages of BenchTOF mass spectrometers for sensitive detection and confident identification.
• See real world examples for robust and repeatable biomarker discovery.

• Prof. George Hanna (Imperial College, London) discuss the challenges involved in developing methods to discover new predictive biomarkers for oesophago-gastric cancer. 
• Learn how Imperial College applied TD–GCxGC–TOF MS/FID for the profiling of  volatiles from biological samples.

• Introduction to GCxGC
• Variable-energy electron ionisation for GCxGC forensic blood VOC profiling
• Identifying the unknown from engine exhaust emissions using GCxGC-ToF-MS and soft EI Innovative
• GCxGC data processing: A tour through ChromSpace