Technical note: Why choose a Time-of-Flight mass spectrometer?
In this technical note, we explore such advantages of TOF MS, specifically SepSolve’s BenchTOF2™ instruments, with examples for both research and routine applications.
This technical note describes the use of Tandem Ionisation for BenchTOF2™ mass spectrometers to acquire both hard (70 eV) and soft (10–20 eV) electron ionisation (EI) in a single analysis.
This technical note demonstrates how Tandem Ionisation data can be used to improve discovery workflows by reducing the frequency of false positives and describes how this is achieved using an untargeted, tile-based approach used in ChromCompare+ software to find the significant class-based differences between GC and GC×GC chromatograms.
SepSolve Analytical, in collaboration with Separation Science, is offering an eSeminar covering the principles and applications of two-dimensional gas chromatography (GC×GC). These presentations are available to view on-demand.
This paper provides a short overview of the theory and practice of the rapidly-developing field of two-dimensional gas chromatography (GC×GC). Included in the discussion are a summary of the detectors used, an assessment of the options available for modulating the first-column eluate, and some recent developments in methodologies for interpreting the results.
This paper provides a short overview of the drawbacks of split/splitless inlets used for GC, and how these can be tackled through large-volume injection (LVI) using the OPTIC-4 multi-mode inlet from GL Sciences.