New cancer biomarkers discovered in breath using 2D GC and TOF MS
Imperial College London, UK
Professor
George Hanna from Imperial College London, UK, identified several predictive
biomarkers for oesophago-gastric and colorectal cancers using GC×GC with
BenchTOF MS
.
Novel predictive biomarkers for cancer have
been identified in breath by researchers at Imperial College London (ICL), UK,
using two-dimensional gas chromatography with time-of-flight mass spectrometry.
The technique enabled them to detect compounds they had not previously seen in
breath samples.
- Customer: Imperial College London, UK
- Application: Breath sample analysis
- Challenge: To improve the discovery of breath biomarkers to
provide new triage procedures
- Solution: Setting up a system consisting of a thermal desorber
with flow-modulated GC×GC and time-of-flight mass spectrometer
- Results: Identification of trace VOCs in breath enabling
discovery of novel biomarkers