Tandem Ionisation

Tandem Ionisation
Tandem Ionisation
Tandem Ionisation
Award-winning Tandem Ionisation enables soft and hard ionisation spectra to be obtained simultaneously in a single run, for both GC and GC×GC analyses, allowing comprehensive characterisation of complex samples with none of the historical hassle associated with soft ionisation.

Exclusive to our BenchTOF2™ mass spectrometers, this patented technique is fully integrated in to analytical workflows, allowing you to increase confidence without increasing analysis time. Using our new tandem file format, both MS data blocks are integrated into one datafile for streamlined processing, to fully benefit from soft EI data in library-searching, quantitation and non-target screening.
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Why should you choose Tandem Ionisation?

  • Identify structurally similar compounds – Use complementary spectra with enhanced molecular ions and reduced fragmentation to identify isomers that are indistinguishable at 70 eV.
     
  • Enhance confidence in identification – Reduce your reliance on retention indices.
     
  • Easily create complementary soft EI spectral libraries with dual-library searching for streamlined use of both 70 eV and soft EI data
     
  • Save time – There are no source-switching or additional variables to optimise, and Tandem Ionisation is fully automated within ChromSpace® software.
     
  • Streamline workflows – Tandem Ionisation data can be used in streamlined discovery workflows to confirm positive hits, thereby reducing the rate of false positives, minimising review time and improving confidence in results.


Applications

Technical note: Improving discovery workflows using Tandem Ionisation® data
This technical note demonstrates how Tandem Ionisation data can be used to improve discovery workflows by reducing the frequency of false positives and describes how this is achieved using an untargeted, tile-based approach used in ChromCompare+ software to find the significant class-based differences between GC and GC×GC chromatograms.
Details
Technical note: Tandem Ionisation – Revolutionary soft ionisation to enhance CONFIDENCE IN IDENTIFICATION
This technical note describes the use of Tandem Ionisation® for BenchTOF2™ mass spectrometers to acquire both hard (70 eV) and soft (10–20 eV) electron ionisation (EI) in a single analysis.
Details
Analysis of complex phthalate mixtures by GC–TOF MS with Select-eV soft ionisation
This study shows how the acquisition of ‘soft’ electron ionisation spectra offers significant advantages for the GC–MS analysis of phthalates.
Details
Determining petrochemical composition by GC×GC–TOF MS/FID: Reliable, automated group-type analysis
This article illustrates how ChromSpace software, in conjunction with dual TOF MS/FID detection and Tandem Ionisation, can streamline the process of achieving robust and reliable analyte speciation and quantitation of complex petrochemicals in an acceptable time frame.
Details
Determining petrochemical composition by GC×GC–TOF MS/FID: The benefits of flow modulation and Tandem Ionisation
This study demonstrates the performance of a flow-modulated GC×GC system for the analysis of complex petrochemicals, with the INSIGHT modulator providing efficient and repeatable modulation without the need for expensive liquid cryogen.
Details
Uncovering trace additives in gasoline
This study demonstrates the use of GC×GC coupled with BenchTOF2 and Tandem Ionisation to identify trace additives in gasoline, with time-saving workflows in ChromCompare+ software utilising all of the tandem data in a single workflow to automatically uncover differences between gasoline blends.
Details
Enhanced characterisation of cannabis extracts using flow-modulated GC×GC–TOF MS/FID with Tandem Ionisation
This study demonstrates the use of flow-modulated GC×GC to detect cannabinoids and terpenoids in complex cannabis extracts, with simultaneous detection by FID for robust quantitation and TOF MS for confident identification (aided by Tandem Ionisation).
Details
Tobacco Smoke Analysis with Tandem Ionisation
This study demonstrates the enhanced separation and unparalleled sensitivity that can be achieved in the characterisation of cigarette smoke, using thermal desorption (TD) and flow-modulated GC×GC with TOF MS, aided by Tandem Ionisation for simultaneous acquisition of NIST-quality 70 eV spectra and complementary soft EI spectra.
Details
Enhanced separation of hop oils by flow-modulated GC×GC–TOF MS
This study demonstrates the high performance of a flow-modulated GC×GC–MS system for the evaluation of complex hop oils, which allows effective modulation of even the most volatile components without the need for expensive liquid cryogen. Analyte speciation is also aided by Tandem Ionisation for simultaneous acquisition of hard and soft EI data.
Details
Detailed characterisation of essential oils by flow-modulated GC×GC and Tandem Ionisation mass spectrometry
In this study, flow-modulated GC×GC–TOF MS with Tandem Ionisation is used to characterise essential oils in fine detail, allowing the in-depth comparison of their compositions that aids rigorous quality control, particularly in the fragrance industry.
Details
Evaluating the authenticity of branded perfumes
This study demonstrates how the comprehensive data acquired using GC×GC–TOF MS with Tandem Ionisation® can be processed in a single, automated workflow to uncover the subtle differences between brand and imitation fragrances.
Details
Investigating the quality of Darjeeling teas using comprehensive VOC fingerprints
This study demonstrates the use of immersive sorptive extraction and GC×GC–TOF MS to determine the characteristic flavour compounds in Darjeeling teas. Comparative analysis of different tea types and grades will be shown using streamlined workflows to improve quality assessment.
Details

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