This study demonstrates the high performance of a flow-modulated GC×GC–MS system for the evaluation of complex hop oils, which allows effective modulation of even the most volatile components without the need for expensive liquid cryogen. Analyte speciation is also aided by Tandem Ionisation for simultaneous acquisition of hard and soft EI data.
The enhanced separation of flow-modulated GC×GC offers confident identification of compounds that would ordinarily co-elute on a 1D GC–MS system. It also enables key compositional differences to be established quickly and routinely, without the need for expensive liquid cryogen.
In addition, the Tandem Ionisation capability of BenchTOF instruments provides additional information that is valuable for analyte speciation, by generating conventional 70 eV and soft-EI spectra simultaneously across every peak.